ob0002p8 | (1) | OU2020
Alexiadou Kleopatra
, Cuenco Joyceline
, Howard James
, Albrechtsen Nicolai Wewer
, Ilesanmi Ibeyimi
, Kamocka Anna
, Tharakan George
, Behary Preeshila
, Ahmed Ahmed R
, Holst Jens J
, Bloom Stephen R
, Khoo Bernard
, Tan Tricia M
Background: Hyperglucagonaemia is one of the key players in the pathophysiology of type 2 diabetes. Roux-en-Y Gastric Bypass (RYGB) is currently a highly effective treatment for weight loss and diabetes remission. However, the role of glucagon in the above effects is unclear.Aim: To characterise the behaviour of proglucagon-derived peptides (glucagon, glucagon-like peptide-1, oxyntomodulin, glicentin) after RYGB surgery.Subjects an...